Improving immunotherapy outcomes in brain cancer

Project title Improving immunotherapy outcomes in brain cancer
Grant Amount
$200,000
Institution
Macquarie University
Investigator Team
Principal investigators Prof. Helen Rizos, Dr. Elena Shklovskaya, Dr. Mark Wong, and Prof. Andrew Davidson, with associate investigators Prof. Jean Yang and Dr. Andreia Vaqueirinho de Pinho
Grant Type
2019 Innovation Grant
Years
2019 – 2021

The team from Macquarie University is renowned for their research into immunotherapy treatments for melanoma patients. Their research has resulted in positive outcomes for melanoma patients with metastatic brain tumours. They also identified similarities between patients with metastatic brain tumours and those with glioblastoma. This grant will allow them to apply this knowledge and expertise into glioblastoma, the most aggressive form of brain cancer. 

This research project will analyse glioblastoma tumours that have been removed in surgery, for immune markers. These markers will identify the patients likely to respond to immunotherapy treatments.  Researchers will also investigate why some patients do not respond to immunotherapy treatment, and design new drug combinations to overcome this. 

“Funding from Cure Brain Cancer Foundation will allow us to systematically apply our established research platform to brain cancer.”

Prof. Helen Rizos