Plan / Design / Master Protocol Development of the International Adaptive Clinical Trial for Glioblastoma

Project title Plan/ Design/ Master Protocol Development of the International Adaptive Clinical Trial for Glioblastoma
Grant Amount
$1.176 million
Institution
Arizona State University
Investigator Team
Principal investigator Dr. Anne Barker
Grant Type
Clinical Trial
Years
2014 – 2016

GBM AGILE is a revolutionary new clinical trial which presents a brand new way of testing and developing brain cancer treatments; a world-first global adaptive clinical trial brought about by the biggest collaboration in the history of brain cancer research. 

Cure Brain Cancer Foundation was a catalyst in designing this new flexible, adaptive clinical trial approach. This approach gives GBM AGILE the potential to fundamentally change the clinical research process, by identifying or disproving therapies for GBM quickly. The aim of this is to help usher in a new generation of effective treatments for GBM, which remains the most common and deadliest type of brain cancer.

“GBM AGILE is more than a clinical trial – it is a movement. A movement that shows silos don’t have to exist in cancer research when the mission far outweighs any reward that can come to an individual scientist… The willingness of two organisations, Arizona State University and Cure Brain Cancer Foundation have served as both the catalysts and the enabling force to transform GBM AGILE from a “big idea” to a point where it can now become reality.”

Progress

Thanks to your support, the GBM AGILE trial is now open to enrolment in six sites across Australia, representing a new chapter for people with glioblastoma (GBM).