Associate Professor Mantamadiotis is the head of the Brain Cancer Biology & Tumour Microenvironment Laboratory, at The University of Melbourne and Doherty Institute, and he sits on the editorial board of the Oxford University Press journal, Carcinogenesis.
Associate Professor Mantamadiotis completed his PhD research training at the Ludwig Institute of Cancer Research in Melbourne and has worked at the DKFZ-German Cancer Research Centre, the Peter MacCallum Cancer Centre, and Monash University. He was also a Marie-Curie Fellow at the University of Patras, Greece, where he began his research on brain cancer, as part of a European Union funded collaborative project. He has published over 100 scholarly works, which have been cited over 5,500 times.
Associate Professor Mantamadiotis’ research highlights include the development of sophisticated mouse models in which brain tumours can be activated at any stage of a mouse’s life, which enables modelling of both paediatric and adult brain cancer. He also leads research using state-of-the-art spatial biology technologies to help understand how cellular and non-cellular components of the complex brain tumour microenvironment communicate to regulate tumour growth. His recent research has uncovered novel mechanisms operating in brain tumours, which could be targeted to enhance a patient’s immune system, to efficiently detect, and effectively kill brain cancer cells.
“With every scientific breakthrough, we move closer to transforming brain cancer from a devastating diagnosis into a manageable condition, providing better quality of life and renewed hope for patients. I’m delighted to be part of Cure Brain Cancer Foundation, helping to accelerate discoveries into ever more effective treatments.”